OPSONIN PHARMA LTD.
Dicycloverine is indicated in: Functional bowel/ irritable bowel syndrome Urinary incontinence secondary to unstable detrusor muscle Infantile colic GIT spasm Colicky abdominal pain Diverticulitis Abdominal colic
Anticholinergics (antimuscarinics)/ Anti-spasmodics
Dicycloverine HCl relieves smooth muscle spasm in the GI and urinary tract. This effect is partly due to antimuscarinic action and partly direct action on the smooth muscle.
Oral dosage forms- Adults:10 to 20 mg three times a day. Children >6 months of age: 5 to 10 mg three times a day. Children <6 months of age: Dose must be determined by the doctor. Oral dicycloverine Hydrochloride should be started as soon as possible Intramuscular dosage form- Adults: Intramuscular injection. Not for intravenous use. The recommended intramuscular dose is 80 mg daily (in 4 equally divided doses). Intramuscular dosage form should not be used for periods longer than 1 or 2 days.
Insomnia, mydriasis, cycloplegia, increased ocular tension, urinary hesitancy, palpitations, dyspnea.
Pregnancy: Category B. Dicycloverine was neither teratogenic nor embryocidal in animal trial. It, like other drugs should be used during pregnancy only if clearly needed. There are no data on the secretion of this drug into breast milk. Dicycloverine should be used cautiously in case of lactating mother.
Toxic reaction seldom occurs with dicycloverine. The signs and symptoms of overdosage are headache; nausea; vomiting; blurred vision; dilated pupils; hot, dry skin; dizziness; dryness of the mouth; difficulty in swallowing; and CNS stimulation.
Use with caution in patients with autonomic neuropathy, hepatic or renal disease, ulcerative colitis, coronary heart disease, congestive heart failure, cardiac tachyarrhythmia, known or suspected prostatic hypertrophy.
Store below 308C.